Global research warns that liver cancer cases could double worldwide by 2050 if no preventive measures are taken.
Current statistics
The Lancet reports, using data from the Global Cancer Observatory, that annual liver cancer cases may rise from 870,000 to 1.52 million. Liver cancer is currently the third leading cause of cancer deaths worldwide. Between 2015 and mid-century, it could claim around 1.37 million lives annually.
Preventable causes
Experts note that about two-thirds of liver cancer cases are preventable. Hepatitis B and C viruses will remain leading causes of liver cancer by 2050. Vaccinating newborns against Hepatitis B is the most effective prevention, but coverage remains low in low-income regions, particularly sub-Saharan Africa. Without stronger vaccination programs, up to 17 million people could die from Hepatitis B between 2015 and 2030.
Lifestyle risk factors
Alcohol consumption may increase liver cancer incidence by over 21% by 2050, a 2% rise from 2022. Obesity-related liver disease may also rise by 2%, affecting about 11% of cases.
Call for global action
The study highlights major gaps in liver cancer prevention and treatment. Experts urge global awareness campaigns, particularly targeting high-risk groups, including those with obesity or diabetes. Early prevention and lifestyle changes are key to reducing liver cancer deaths.





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